- (month unknown)
- Nintendo of America and Disney Interactive announce a thirteen-title deal for Nintendo to publish a series of Nintendo 64 and Game Boy Color games using Disney characters. [404.114]
- Konami releases the NHL Blades of Steel '99 video game for the Nintendo 64 in the US. [235.74]
- March
- All-Nippon Airlines introduces Pokémon-decorated airplanes for select flights between Tokyo and the US. [595.142]
- In San Jose, California, the 13th annual Game Developers Conference is held. The Computer Game Developers' Association holds its Spotlight Award ceremony.
- Most innovative game: Legend of Zelda: Ocarina of Time.
[592.31] [1291.42]
- March 28
- The Fox Broadcasting Company airs the Futurama TV show in the US. An arcade video game is played, Monkey Fracas Jr., with a space ship fighting a giant ape throwing barrels pulled from inside a planet. This is a reference to the video game Donkey Kong Jr.. [840]
- March (month)
- Top selling video game in the USA for the month: Pokémon Blue Version for the Game Boy. [1095.32]
- Top selling Nintendo 64 video game in the USA for the month: Mario Party. [1095.32]
- Top selling Game Boy Color video game in the USA for the month: The Legend of Zelda DX: Link's Awakening. [1095.32]
- April 26
- Nintendo releases the Super Smash Bros. game for the Nintendo 64 in the US. [304.126] [359.134] [401] [440.42] (May [554.17])
- April 30
- Activision releases the A Bug's Life video game for the Nintendo 64 in the USA. [235.122] [411]
- April (month)
- Top selling Nintendo 64 video game in the USA for the month: Mario Party. [1096.30]
- (month unknown)
- Unit sales of the Nintendo 64 video game system worldwide to date: 24 million. [379.66]
- May 1
- Nintendo releases the Super Mario Bros. Deluxe video game for the Game Boy Color in the US. [401]
- May 12
- Nintendo announces its next-generation console, code-named "Dolphin". It will use a 400 MHz "Gekko" processor developed with IBM, based on the PowerPC processor. [597] [1096.28]
- May 13
- Interact Accessories releases the Sharkwire Online kit for the Nintendo 64. The kit includes a modem cartridge, keyboard, telephone cord, and Spyglass Device Mosaic Web browser. Users can then access the Internet to send and receive email and browse Web sites. [597]
- May 16
- The Fox Broadcasting Company airs The Simpsons TV show in the US. A handheld video game resembling the original Nintendo Game Boy is used on an airplane, interfering with the plane's controls. [878]
- May 19
- LucasArts releases the Star Wars Episode 1: Racer video game for the Nintendo 64 in the US. [440.43] [643.116] [1094.40]
- May
- Sega Enterprises president Shoichiro Irimajiri announces the company will soon sell games for the Game Boy Color in Japan. [1097.30]
- May 31
- Kemco releases the Shadowgate: Trials of the Four Towers video game for the Nintendo 64. [235.125] [411]
- May (month)
- Top selling video game in the USA during the month: Super Smash Bros. for the Nintendo 64. [1097.30]
- June 1
- Nintendo releases the Pokémon Pinball video game for the GameBoy in the US. [401] [405.100] [554.17] [595]
- June
- Nintendo announces a new joint venture in Japan for an online network for the Nintendo 64 to access the Internet, play online tournaments, download new software to the 64DD disk drive. [1097.30]
- Nintendo announces it will sell telecommunications software in Japan to link the Game Boy to cell phones, to download and play games. [1097.30]
- June (month)
- Top selling video game in the USA for the month: Star Wars Episode I: Racer for the Nintendo 64. [1098.34]
- July 1
- Nintendo releases the Pokémon Snap video game for the Nintendo 64 in the US. Price is US$49.95. [401] [405.100] [417.81] [440.43] [595.142] (June 30 [411])
- July 10
- Nintendo releases The New Tetris video game for the Nintendo 64 in the US. [401]
- July
- Nintendo releases the Command & Conquer video game for the Nintendo 64 in the United Kingdom. [393.28] (May [411])
- Nintendo releases the Star Wars Episode 1: Racer video game for the Nintendo 64 in the United Kingdom. [393.28]
- July 27
- Nintendo releases the Mario Golf 64 video game for the Nintendo 64 in the US. [401] [411] [871.38] (August [554.17])
- August
- Retro Studios officially begins work on Metroid Prime video game for the next Nintendo video game system (GameCube). [436.48]
- Nintendo reduces the suggested retail price of the Nintendo 64 in the USA to US$99.95. [1098.32]
- Infogrames releases the Premier Manager 64 video game for the Nintendo 64 in the United Kingdom. [393.28]
- Activision releases the Quake II video game for the Nintendo 64 in the United Kingdom. [235.123] [393.28]
- August 27
- In Tokyo, Japan, the Space World '99 show is held. Nintendo reveals the 64DD, an attachment to the Nintendo 64 allowing storage of game data and access to the Internet. [393.9,13] [819.25]
- August
- In Tokyo, Japan, the Game of the Year ceremony is held. The Fresh Prize is awarded to Nintendo for the Pikachu Genki Dechu video game. The Visual Prize is a tie between The Legend of Zelda: Ocarina of Time for the Nintendo 64 and Final Fantasy VIII for the PlayStation. Second place for Game of the Year is The Legend of Zelda: Ocarina of Time. [393.13]
- August 31
- Year to date sales of the Game Boy and Game Boy Color in the USA: 2.68 million. [1100.34]
- Atari Games releases the Gauntlet Legends video game for the Nintendo 64. [235.125] [411] [418.28] (September [554.17])
- August (month)
- Top selling Nintendo 64 video game in the USA for the month: Pokémon Snap. [1099.40]
- Top selling Game Boy Color video game in the USA for the month: Pokémon Pinball. [1099.40]
- Top selling Game Boy video game in the USA for the month: Pokémon Blue. [1099.40]
- (month unknown)
- Sales of Zelda: Ocarina of Time video game for the Nintendo 64 to date: US$137 million. [378.58]
- Unit sales of video game systems in North America to date: Nintendo Entertainment System 35 million, Super Nintendo 20 million. [378.59]
- Unit sales of the Nintendo Game Boy video game system worldwide to date: 80 million. [378.60] [597]
- September
- Ubi Soft releases the Racing Simulation - Monaco Grand Prix video game for the Nintendo 64 in England. [393.21]
- Acclaim releases the WWF Attitude video game for the Nintendo 64 in the United Kingdom. [393.28]
- Acclaim releases the Shadowman video game for the Nintendo 64 in the United Kingdom. [393.28]
- September 23
- Enix releases the Dragon Quest I & II Remix game for the Game Boy Color in Japan. [298.51]
- September (month)
- Top selling Nintendo 64 video game in the USA for the month: Pokémon Snap. [819.22] [1100.36]
- Top selling Game Boy Color video game in the USA for the month: Pokémon Pinball. [819.22]
- October 1
- Nintendo releases the Pokémon Yellow Version: Special Pikachu Edition video game for the Game Boy Color in the US. (1 million copies sell in 14 days, making it the fastest selling Nintendo title.) [401] [447.4] [554.17] [595.143] [819.154] [1317.30]
- Nintendo releases the Mario Golf video game for the Game Boy Color. [304.126] [401]
- October 8
- The Duke Nuken - Zero Hour video game is released for the Nintendo 64 in England. [393.13]
- October
- Nintendo releases a limited edition Game Boy Color decorated with Pokémon characters, bundled with the video game Pokémon Yellow Version: Special Pikachu Edition. Price is US$109.95. [595.143] [819.154]
- Nintendo releases the Pokémon Red version and Pokémon Blue version games for the Game Boy in Europe. [595.143]
- October 22
- The 33rd annual Tokyo Motor Show is held in Tokyo, Japan. Nintendo demonstrates a Panasonic in-car game system allowing the Nintendo 64 to connect to a mini television in the car. [820.24]
- October 31
- Capcom releases the Resident Evil 2 video game for the Nintendo 64. [411]
- October (month)
- Top selling video game in the USA for the month: Pokémon Yellow for the Game Boy Color. [753.42]
- Top selling Nintendo 64 video game in the USA for the month: Pokémon Snap. [753.42]
- November 10
- Warner Bros. releases the film Pokémon: The First Movie to theaters. (The Pokémon characters originated with a video game in Japan. Total American theater ticket sales: US$86 million.) [440.43] [447.4] [463.293] [493.29] [496.40] [595.143] [819.154]
- November 15
- Nintendo releases the Donkey Kong 64 video game for the Nintendo 64 in the US. Included within the game is the original Donkey Kong video game. [393.28] [401] [411] [819.135] [1099.61]
- November
- Nintendo releases the Pokémon Gold and Pokémon Silver video games for the Game Boy Color in Japan. [595.143]
- Time magazine in the US features the Pokémon characters on its cover. [595.143]
- THQ releases the Wrestlemania 2000 video game for the Nintendo 64 in the US. [1218.82]
- Nintendo releases the Donkey Kong Set, including Jungle Green Nintendo 64 system, Donkey Kong 64 Game Pak, Jungle Green Controller, and Expansion Pak. [446.52]
- November (month)
- Top selling video game in the USA for the month: Pokémon Yellow for the Game Boy. [753.42]
- Top selling Nintendo 64 video game in the USA for the month: Donkey Kong 64. [753.42]
- December 1
- Nintendo releases the 64DD disk drive for the Nintendo 64 in Japan. Included are a modem cartridge, Kyojin no Doshin (Doshin the Giant) video game, and Mario Artist: Paint Studio software. (Total sales over the product's lifetime: about 250,000.) [393.45] [825.32] [1151.44]
- December
- Unit sales of the Nintendo 64 video game system worldwide to date: 28.7 million. [377.62]
- December 31
- Unit shipments of Nintendo's Mario Party video game in the USA to date: 1.15 million. [597]
- October-December
- Market share of shipments of video game systems in the US during October to December: PlayStation 49.1%, Nintendo 64 32.1%, Dreamcast 18.8%. [748.202]
- Year
- Market share of video game systems in the US: PlayStation 34%, Game Boy 31%, Nintendo 64 17.5%, Dreamcast 16%. [684.17]
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